Abbey End is undergoing big change with the loss of long-standing businesses and high expectation for new shops and eateries.
The Treehouse Bookshop and neighbouring Town and Country Furniture both closed their doors for the last time at the end of December.
While both businesses continue to trade in new premises, The Shakespeare Hospice will move into the former furniture shop in April.
The hospice is seeking staff for the new furniture shop, with applications for drivers, sales assistants and a manager now being advertised.
The Stratford-based charity offers in-home care services across Kenilworth - and hopes the new venture will help raise the £1.8million needed each year to make its services possible.
Adrienne Rostron, head of retail at the charity, said: “We are looking forward to coming to Kenilworth and being part of the community, working with and supporting local organisations and activities.”
Victoria Mier from The Treehouse Bookshop is calling for help to find new premises in the town to run the community venture and host live music and literature events.
There are also changes to the former Jade Restaurant and Blockbuster Video sites which will reopen as a pub in the coming weeks.
A new wine bar and art gallery has opened in Smalley Place, and Indian Edge has almost completed its expansion along Warwick Road.
Marco Pierre White is still set to open a restaurant in the Holiday Inn in what Chamber of Trade chairman, Richard Hales, said was “very exciting” to keep shoppers visiting.